Hypochlorous Acid in Skincare
Written by the Skin Happy team. 20 Jan 2025.
When it comes to skincare, hypochlorous acid (HOCl) is a game-changer. But what exactly is it, and why is it so effective?
Let’s explore the science behind this remarkable compound and discover how it helps calm irritation, fight breakouts, and support your skin’s natural healing — all while keeping your routine simple and effective.
The Basics of Hypochlorous Acid
Hypochlorous acid (HOCl) is a weak acid and antimicrobial molecule naturally produced by your body. Your immune system creates HOCl within white blood cells to defend against harmful bacteria, viruses, and other pathogens. Amazing, right? It’s part of why your body fights infections so effectively.
In chemical terms, hypochlorous acid is HOCl, consisting of one hydrogen (H), one oxygen (O), and one chlorine (Cl) atom. Despite its simple structure, HOCl is incredibly effective at neutralising harmful microbes while being gentle on human cells.
How Does Hypochlorous Acid Work?
The effectiveness of HOCl lies in its ability to disrupt the outer layers of microorganisms. Here’s how it works:
Microbial Cell Disruption: HOCl penetrates the protective membranes of pathogens, reacting with proteins, lipids, and nucleic acids. This oxidative damage breaks down the cell’s structure, leading to its destruction.
Oxidative Burst: It reacts with vital cellular components, such as enzymes and DNA. For example, HOCl oxidises sulfhydryl groups (-SH) in proteins, rendering them inactive and halting the pathogen’s metabolism.
Neutralising Harmful Substances: HOCl also neutralises toxins and irritants produced by bacteria, making it excellent for soothing inflamed or irritated skin.
Why Hypochlorous Acid is Safe for Humans
Unlike many disinfectants, hypochlorous acid is non-toxic and gentle on human cells. Our cells are naturally equipped to tolerate HOCl—it’s part of our immune system! Pathogens, however, lack this tolerance, making HOCl an effective and targeted defence.
The Chemistry Behind It
Let’s break it down:
HOCl is formed when chlorine (Cl2) dissolves in water and undergoes hydrolysis: Cl2 + H2O → HOCl + HCl
In solution, hypochlorous acid exists in equilibrium with its conjugate base, hypochlorite (OCl-): HOCl ⇌ H+ + OCl-
The balance depends on pH. In slightly acidic to neutral conditions (pH 4-7), HOCl dominates and is highly effective as an antimicrobial agent.
Benefits of Hypochlorous Acid in Skincare
Hypochlorous acid provides numerous benefits to both face and body, such as:
Calming Skin Irritation: Soothes redness, reduces inflammation, and eases irritation.
Neutralising Bacteria: Effective against germs that can cause breakouts or infections.
Post-Workout Care: After sweating, it helps refresh the skin and prevent irritation.
Enhancing Skin Barrier: Supports your skin’s natural defences for a healthy glow.
Gentle on Skin: Perfect for sensitive skin types.
Applications in Everyday Life
Skincare
One of the standout benefits of hypochlorous acid is how gentle it is on your skin. It:
Cleanses and purifies
Reduces redness
Calms and soothes irritation
Improves skin texture
Prepares skin for treatments
Eases itchiness
Helps heal cuts and scrapes
Clears congestion
Helps control odour
Refreshes skin
Provides relief
Boosts hydration
Supports the skin barrier
Promotes healthier-looking skin.
If you’ve just had a sweaty workout or your skin feels stressed, a quick spritz of an HOCl-based product can refresh and soothe your complexion — without stinging or harsh chemicals. The Skin Happy Hypochlorous Acid Facial Spray is perfect after an intense gym session or a day in the sun. Sweating and environmental toxins can leave your skin prone to breakouts, but Skin Happy neutralises bacteria, calms redness, and leaves your skin feeling cool and clean.
Tool Sanitisation
HOCl is also ideal for sanitising skincare tools and equipment. It effectively eliminates harmful bacteria and keeps your tools safe for reuse without harsh chemicals.
Concentration Levels & Recommended Usage
The recommended concentration of HOCl in skincare products is typically low, ranging from 0.005% to 0.02% hypochlorous acid. This concentration range provides benefits such as antimicrobial, anti-inflammatory, and wound care properties. Here’s why:
Effectiveness: Low concentrations are sufficient to deliver desired results without causing irritation.
Safety: Higher concentrations may lead to skin irritation due to increased sodium hypochlorite levels, which are in equilibrium with HOCl.
Applications: While higher concentrations are used in disinfectants, skincare formulations stay within the safe and effective range for daily use.
Are There Any Ingredients That Should Not Be Used with Hypochlorous Acid?
Hypochlorous acid is sensitive to light, heat, and pH changes. For skincare products containing HOCl to remain stable and effective:
Purity Matters: Only very pure salt and minimal metallic ion impurities should be used during the electrolysis process. Impurities can reduce the shelf life and stability of HOCl.
Manufacturing Considerations: Equipment used during production must avoid materials like metal, which can oxidise or rust in the presence of HOCl.
Avoid Mixing: Do not mix HOCl-based sprays with other personal care products before applying them to the skin. This can reduce their efficacy.
For best results, apply hypochlorous acid first, let it dry, and then layer other skincare products.
Frequently Asked Questions
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Yes! Hypochlorous acid is incredibly gentle and perfect for sensitive skin types, including those with eczema or redness. Its soothing and non-toxic properties make it ideal for calming irritation without causing further dryness or damage.
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Absolutely. Hypochlorous acid sprays are safe for daily use. In fact, regular application can help maintain skin hygiene, reduce redness, and support your skin’s natural barrier.
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HOCl is great for:
Individuals with sensitive or acne-prone skin.
People looking for a gentle post-workout skin refresher.
Anyone seeking a natural, effective way to calm irritation or redness.
While hypochlorous acid is safe for most people, those with specific allergies to chlorine-based compounds should consult a healthcare professional before use.
Why Choose Hypochlorous Acid?
Skin Happy’s HOCl spray is formulated with 0.02% pure hypochlorous acid at a skin-friendly neutral pH — a balance that supports effective cleansing while remaining gentle on the skin. It’s suitable for use after workouts, to help calm irritation, reduce redness, and support clearer skin.
Designed with active lifestyles in mind, this formulation offers a practical way to refresh and care for your skin on the go. Backed by science and made with naturally derived ingredients, it’s a straightforward addition to any skincare routine looking for a gentle yet effective option.
Disclaimer: This article is intended to educate readers on specific ingredients and skincare topics. The information provided is for educational and informational purposes only. Please note that Skin Happy products containing hypochlorous acid are formulated for cosmetic use only and are not intended as replacements for physician advice or pharmaceutical product recommendations.